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Detail Information


Basic information:


Untranslated mRNA: Sponge mRNA

Related IDs cncRNA ID CNC_M_001691
Name MYC
Gene ID 4609
Location Coordinate(Strand) 8:127735434-127742951(+)
Locus Sequence
Organism Homo sapiens

Evidence support:

  
In vivo/vitro assay In vitro assay
Low-throughput method Transfection assay;Western blotting;qRT-PCR;Luciferase assay;Cell proliferation assay;FACS analysis
High-throughput method /
Tissue/Cell NB4 cell;Leukemia sample
Description of experimental evidence The mRNA was detected by transfection assay, western blotting, qRT-PCR and luciferase assay in NB4 cell, which can bind let-7c, let-7g, let-7a,acting as a competing endogenous RNA in acute promyelocytic leukemia.

Orthologues:

  
Chimpanzee ENSPTRG00000020581  
Mouse ENSMUSG00000022346  
Drosophila /
Zebrafish ENSDARG00000045695   ENSDARG00000007241  

References:

  
PMID 27486764
Description In our study, we demonstrate that expression of PML/RARa, the APL-associated fusion oncogene is repressed by c-Myc mRNA transcript independent of protein-coding function but dependent upon microRNA.

Related Subcelluar Localization:

  
Subcelluar Localization RLID Link to RNALocate
chromatin RLID00081312 Link to RNALocate
cytosol RLID00081313 Link to RNALocate
cytosol RLID00081314 Link to RNALocate
nucleolus RLID00081315 Link to RNALocate
nucleoplasm RLID00081316 Link to RNALocate
nucleus RLID00081317 Link to RNALocate
nucleus RLID00081318 Link to RNALocate
exosome RLID00081319 Link to RNALocate
Cytosol RLID00013512 Link to RNALocate
Ribosome RLID00013513 Link to RNALocate
Nucleus RLID00013514 Link to RNALocate
Cytosol RLID00013515 Link to RNALocate

Related Diseases:

  
OMIM Phenotype Phenotype MIM number Link to OMIM
Burkitt lymphoma, somatic OMIM:113970 Link to OMIM

Related Interactions:

  

  

   Notes: You can browse the related interactions in RNAinter by click the above link (since the interaction entries are too much to show here).